You may need to stop using Simcor for a short time if you have:Īn electrolyte imbalance (such as high or low potassium levels in your blood) Follow the label directions or your doctor's instructions about how much aspirin to take. Do not take aspirin without your doctor's advice. Your doctor may recommend you take aspirin 30 minutes before you take Simcor to prevent certain side effects. These effects should disappear over time as you keep taking the medicine. These effects can be made worse if you drink alcohol or hot beverages shortly after you take Simcor. Niacin can cause certain side effects such as dizziness, sweating, chills, flushing (warmth, redness, or tingly feeling under your skin), fast or pounding heartbeats, shortness of breath, or feeling like you might pass out. Do not take this medicine on an empty stomach.ĭo not crush, chew, or break an extended-release tablet. Simcor is usually taken at bedtime with a low-fat snack. Taking too much of this medication may cause serious or life-threatening side effects. Never take this medicine in larger amounts, or for longer than recommended by your doctor. Follow all directions on your prescription label. Simcor pregnancy and breastfeeding warnings (more detail) How should I take Simcor? Do not breastfeed while you are taking niacin and simvastatin. Niacin and simvastatin may pass into breast milk and could harm a nursing baby. Use effective birth control to avoid pregnancy while you are taking this medicine. Stop taking this medication and tell your doctor right away if you become pregnant. Simcor can harm an unborn baby or cause birth defects. Or if you are switched to this medication from regular niacin, nicotinic acid, or nicotinamide (or vitamin supplements that contain niacin). If you drink more than 2 alcoholic beverages daily To make sure Simcor is safe for you, tell your doctor if you have ever had: HIV or AIDS medication - atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, tipranavir.īefore you start taking Simcor, tell your doctor if you are already using any of these other medicines: Hepatitis C medications - boceprevir, telaprevir or Heart or blood pressure medicine - amiodarone, diltiazem, verapamil These drugs should not be used while you are taking Simcor:Īn antibiotic - clarithromycin, erythromycin, telithromycin Īntifungal medicine - fluconazole, itraconazole, ketoconazole, posaconazole The following drugs can increase your risk of serious muscle problems if you take them together with simvastatin. This condition may be more likely to occur in women and older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid). Simvastatin can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. You should not take Simcor if you are allergic to niacin (Niaspan, Niacor, and others) or simvastatin (Zocor, Vytorin), or if you have: The following drugs should not be used while you are taking Simcor: cyclosporine, danazol, nefazodone, gemfibrozil clarithromycin, erythromycin, telithromycin fluconazole, itraconazole, ketoconazole, posaconazole amiodarone, diltiazem, verapamil boceprevir, telaprevir atazanavir, cobicistat, darunavir, delavirdine, fosamprenavir, indinavir, nelfinavir, ritonavir, saquinavir, or tipranavir. You should not take Simcor if you are allergic to niacin or simvastatin, or if you have liver disease, stomach ulcer, or severe bleeding.ĭo not breast-feed while using this medicine. Simvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Simvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL). Niacin is also present in many multiple vitamins and nutritional supplements. It occurs naturally in plants and animals, and is also added to many foods as a vitamin supplement. Niacin, also called nicotinic acid, is a B vitamin (vitamin B3). Simcor is used along with diet to lower levels of total cholesterol, LDL "bad" cholesterol, and triglycerides and to increase HDL "good" cholesterol. Simcor is used to lower cholesterol and triglycerides (types of fat) in the blood. Simcor contains a combination of niacin and simvastatin. Medically reviewed by Philip Thornton, DipPharm. Generic name: niacin and simvastatin ĭrug class: Antihyperlipidemic combinations
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